银杏内酯 A
银杏内酯A(Ginkgolide A)
CAS: 15291-75-5
化学式: C20H24O9
| 中文名 | 银杏内酯A |
| 英文名 | Ginkgolide A |
| 别名 | 银杏内酯A 银杏苦内酯A 银杏内酯 A 白果苦内酯 A GI银杏内酯A 银杏内酯A(标准品) 银杏内酯 A, 来源于银杏 银杏内酯 A 来源于银杏 叶 |
| 英文别名 | lide A BN-52020 BN 52020 Ginkgolide A GINKGOLIDE A PRIMULIC ACID 1 1,7-DIDEOXYGINKGOLIDE C GINKGOLIDE A, GINKGO BILOBA L GINKGOLIDE A FROM GINKGO LEAVES |
| CAS | 15291-75-5 |
| EINECS | 604-873-4 |
| 化学式 | C20H24O9 |
| 分子量 | 408.4 |
| InChI | InChI=1/C20H24O9/c1-7-12(22)26-10-6-17-9-5-8(16(2,3)4)18(17)11(21)13(23)28-15(18)29-20(17,14(24)27-9)19(7,10)25/h7-11,15,21,25H,5-6H2,1-4H3/t7-,8+,9-,10+,11+,15+,17?,18?,19-,20?/m1/s1 |
| InChIKey | FPUXKXIZEIDQKW-VKMVSBOZSA-N |
| 密度 | 1.56±0.1 g/cm3(Predicted) |
| 熔点 | 280°C (dec.) |
| 沸点 | 710.1±60.0 °C(Predicted) |
| 比旋光度 | D24 -53.4° (c = 1 in ethanol) |
| 闪点 | 256.5°C |
| 蒸汽压 | 2.69E-23mmHg at 25°C |
| 溶解度 | 溶于DMSO |
| 折射率 | 1.631 |
| 酸度系数 | 11.45±0.70(Predicted) |
| 存储条件 | Inert atmosphere,Store in freezer, under -20°C |
| 外观 | 整洁 |
| 颜色 | White to Off-White |
| 最大波长(λmax) | ['219nm(EtOH)(lit.)'] |
| 物化性质 | 白色结晶体，易溶于甲醇、丙酮，不溶于水，来源于银杏叶。 |
| MDL号 | MFCD00133365 |
| 体外研究 | Ginkgolide A (BN-52020) is a highly active PAF antagonist cage molecule that is isolated from the leaves of the Ginkgo biloba tree. Shows potential in a wide variety of inflammatory and immunological disorders. Ginkgolide A (BN-52020) failed to affect apoptotic damage neither in serum-deprived nor in staurosporine-treated neurons. |
| 体内研究 | Ginkgolide A significantly shortened the sleeping time in anesthetized mice. |
| 安全术语 | 24/25 - 避免与皮肤和眼睛接触。 |
| WGK Germany | 3 |
| RTECS | KC9943000 |
| FLUKA BRAND F CODES | 10 |
| 海关编号 | 29322090 |
| 参考资料 展开查看 | 1. 冯如 李泽宏 袁红慧 等. 不同胁迫处理对银杏叶片萜内酯含量的影响[J]. 武汉工业学院学报 2017 036(001):34-38 53. 2. 张相伦, 吴大伟, 陆鹏,等. 普通和超微粉碎对银杏叶黄酮和萜内酯释放规律的影响研究[J]. 粮食与饲料工业, 2014, 12(006):45-47. 3. 刘志双, 郑玉粉, 孙红娜,等. 银杏叶提取物对4种口服抗凝药抗凝活性的影响. 4. Zhang, Wen, et al. "Diterpene ginkgolides protect against cerebral ischemia/reperfusion damage in rats by activating Nrf2 and CREB through PI3K/Akt signaling." Acta Pharmacologica Sinica 39.8 (2018): 1259-1272.https://doi.org/10.1038/aps.2017.149 5. Zhang, Xianglun, et al. "Effect of Ginkgo biloba Leaf Powder on Growth Performance, Meat Quality and Antioxidant Activity of Muscle in Growing-Finishing Pigs." Pakistan Journal of Zoology 48.5 (2016). 6. Zhang, Xianglun, et al. "Effect of Ginkgo biloba Leaf Powder on Growth Performance, Meat Quality and Antioxidant Activity of Muscle in Growing-Finishing Pigs." Pakistan Journal of Zoology 48.5 (2016). 7. [IF=5.064] Zhang Wen et al."Diterpene ginkgolides protect against cerebral ischemia/reperfusion damage in rats by activating Nrf2 and CREB through PI3K/Akt signaling."Acta Pharmacol Sin. 2018 Mar;39(8):1259-1272 8. [IF=3.935] Xingliang Niu et al."Hydrogen/deuterium exchange, a unique and effective method for MS fragmentation behavior elucidation of ginkgolides and its application to systematic research in Ginkgo biloba."J Pharmaceut Biomed. 2017 Feb;134:181 9. [IF=9.297] Minmin Zou et al."Removal of ginkgotoxin from the Ginkgo biloba seeds powder by adopting membrane separation technology."J Clean Prod. 2021 Jan;280:124452 10. [IF=5.645] Ying Guo et al."Spatial prediction and delineation of Ginkgo biloba production areas under current and future climatic conditions."Ind Crop Prod. 2021 Aug;166:113444 11. [IF=4.36] Xiao-Xue Fan et al."Diterpene Ginkgolides Meglumine Injection inhibits apoptosis induced by optic nerve crush injury via modulating MAPKs signaling pathways in retinal ganglion cells."J Ethnopharmacol. 2021 Oct;279:114371 12. [IF=3.638] Wen Zhang et al."Efficient removal of ginkgotoxin from Ginkgo biloba seed powder by combining endogenous enzymatic hydrolysis with resin adsorption."J Sci Food Agr. 2021 Mar;101(4):1589-1597 13. [IF=5.645] Qihui Dong et al."Solubilization of phytocomplex using natural deep eutectic solvents: A case study of Ginkgo biloba leaves extract."Ind Crop Prod. 2022 Mar;177:114455 14. [IF=3.935] Yongyi Li et al."Integrated molecular networking strategy enhance the accuracy and visualization of components identification: A case study of Ginkgo biloba leaf extract."J Pharmaceut Biomed. 2022 Feb;209:114523 |
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产品名: 银杏内酯杂质6(银杏内酯A) 去供应商网站查看 询盘CAS: 15291-75-5
产地: 中国-STD
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规格: 10mg，25mg，50mg，100mg
价格: 电询
库存: 现货
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产品名: 银杏内酯A(10mM in DMSO,无菌) 去供应商网站查看 询盘CAS: IG01301
产地: 北京
包装: 1ml/瓶
规格: IG01301-1ml
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库存: 现询
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现货供应
产品名: 银杏内酯杂质6(银杏内酯A) 去供应商网站查看 询盘CAS: 15291-75-5
产地: 中国-STD
包装: 支
规格: 10mg，25mg，50mg，100mg
价格: 电询
库存: 现货
电话: 0714-3999186
手机: 15671228036
电子邮件: 2853786052@qq.com
QQ: 2853786052
微信: 15671228036
产品描述: 6266S
提供多种规格现货供应
产品名: 银杏内酯A(10mM in DMSO,无菌) 去供应商网站查看 询盘CAS: IG01301
产地: 北京
包装: 1ml/瓶
规格: IG01301-1ml
价格: 电话、微信、QQ、邮件
库存: 现询
电话: 010-50973130
手机: 17801761073(微信同号)
电子邮件: 3193328036@qq.com
QQ: 3193328036
微信: 17801761073
产品描述: 索莱宝直销,欢迎来询
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